| ncRNA name | hsa-miR-93 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples, normal retinas; RB cell lines Y79 and WERI-RB1 |
| Methods | microarray, transfection, qPCR, MTT assay, immunoblot, flow cytometry, scratch assay |
| Expression pattern | up-regulated |
| Functional description | The regulatory targets of miR-106b∼25 cluster namely p21 (cyclin-dependent kinase inhibitor) and BIM (pro-apoptotic gene) were elevated, and apoptotic cell death was observed, in RB tumor cells treated with the specific antagomirs of the miR-106b∼25 cluster. Thus, suppression of miR-106b∼25 cluster controls RB tumor growth. |
| PubMed ID | 25232279 |
| Year | 2014 |
| Title | Integrated Analysis of Dysregulated miRNA-gene Expression in HMGA2-silenced Retinoblastoma Cells. |
| Drug-related ncRNA | NO |
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